Antibacterial Activities Of Carica Papaya Seed Against Enteric Organisms

Fruit and seed extracts have antibacterial activity against Bacillus cereus, Escherischia coli, and Pseudomonas aeuroginosa (Tang et al., 1972; Emeruwa et al., 1982). The juice is used for curing warts, cancer, and tumors. Leaves have beenpoulticed into nervous pains, elephantoid growths (Asolkar et al., 1992). The antihyperglycemic effect of unripe mature fruits and seeds of Carica papaya have also been reported (Olagunja, et al 1995; Adeneye and Olagunja, 2009).

Papaya leaves are made into tea as a treatment for malaria. Antimalarial and antiplasmodial activity has been noted in some preparations of the plant, the leaves of the papaya plants contain chemical compounds of karpain, Substance which kills microorganisms that often interfere with the digestive function (Udoh et al., 2005). Papaya leaf extracts have phenolic compounds, such as protocatechuic acid, p-coumaric acid, 5, 7- dimethoxycoumarin, caffeic acid, kaempferol, quercetin, chlorogenic acid (Romasi et al., 2011).Antimicrobials of plant origin effective in the treatment of infectious diseases and simultaneously mitigating many of the side effects often associated with synthetic antimicrobial agents have been discovered. Medical uses of plants range from the administration of the roots, barks, stems, leaves and seeds to the use of extracts and decoction from the plants (Iwu et al., 1999).

1.1 AIM

To determine the antibacterial effect of Carica papaya seed on enteric microorganism.

1.2 OBJECTIVES

To extract the active ingredients from Carica papaya seeds using two different solvents (water and methanol)

To determine the potency and efficacy of aqueous and methanolic seed extract of Carica papaya seed.