• ANTIMICROBIAL EFFECTS OF THREE SPECIES OF Mangifera indica


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    • ABSRACT - [ Total Page(s): 1 ]There have been reports of increasing development of drug resistance among human pathogens as well as undesirable side effects of certain antimicrobial agents. It is therefore necessary to search for new agents that are better, cheaper and without side effects for treating infectious diseases especially in developing countries. In this research study, three sub-species (Kerosene, German and Sheri) of Mangifera indica leaf extracts were examined to ascertain which has more antimicrobial effect against the test organisms. The test organisms were Staphylococcus aureus, Pseudomonas aeruginos ... Continue Reading

         

      TABLE OF CONTENTS - [ Total Page(s): 1 ]TITLE PAGE     APPROVAL PAGE     DEDICATION                                 ACKNOWLEDGEMENTS                                     ABSTRACT     TABLE OF CONTENTS                                         LIST OF TABLES         LIST OF FIGURES         CHAPTER ONE                                         1.0    INTRODUCTION         1.1 AIMS 1.2 JUSTIFICATION                     1.3 LITERATURE REVIEW                     ... Continue Reading

         

      CHAPTER ONE - [ Total Page(s): 2 ]1.0 INTRODUCTION Continuous spread of infectious diseases is a major apprehension for health institutions, pharmaceutical companies and government think tanks all over the world. Failure of treatment, particularly with the current escalating trends of multi-drug resistance (MDR) to the available modern drugs or antibiotics among emerging and re-emerging bacterial pathogens leads to serious risks (Olasehinde et al., 2016). Around 1900, 80% of the drugs were derived from plants, however, in the decades that followed, the development of synthetic drugs from petroleum products caused a sharp de ... Continue Reading

         

      CHAPTER TWO - [ Total Page(s): 1 ]MATERIALS AND METHOD 2.0 Plant Materials Three varieties of Mangifera indica leaves were gotten from Nsukka area, Enugu state. The leaves were from species locally known as -Kerosene mango, -German mango, and -Sheri mango (sweet mango), respectively. The Sheri mango produces fruits smaller than the first two.   2.1 Preparation of plant materials The leaves were washed for dust with tap water and rinsed with distilled water. They were dried under shade (at room temperature) for 10 days. After drying, the leaves were crushed into a powdered form with a sterile grinding machine. T ... Continue Reading

         

      CHAPTER THREE - [ Total Page(s): 1 ]3.1 RESULTS At the end of the research experiment, it was ascertained that the aqueous extracts of the three sub-species of Mangifera indica was not effective in causing inhibition in the three test organisms used. In the case of the ethanolic extract of the three sub-species, there was visible inhibition, which varied with the Mangifera sub-species and with the different organisms. The results of both the aqueous and ethanolic extracts are represented in Table 3.1 and 3.2 respectively.   Table 3.1: Antimicrobial activity of aqueous leaf extract of three sub-species of Mangifera indi ... Continue Reading

         

      CHAPTER FOUR - [ Total Page(s): 1 ]DISCUSSION AND CONCLUSION 4.1 DISCUSSION Several studies has suggested that extracts of various part of plant Mangifera indica L. show a protective effect on different human pathologies. In particular, this extract acts as scavenger of free radical and consequently may exhibit beneficial pharmacological effects in several pathologies in which oxidative stress plays a major role (Guiseppe et al., 2019). The basic parameters influencing the quality of an extract are plant parts used as a starting material, the solvent used for extraction, the extraction technology and sterilisation meth ... Continue Reading

         

      REFRENCES - [ Total Page(s): 1 ]REFERENCES   Abbasi, A. M., Guo, X., Fu, X., Zhou, L., Chen, Y., Zhu, Y., et al. (2015). Comparative Assessment of Phenolic Content and in Vitro Antioxidant Capacity in the Pulp and Peel of Mango Cultivars. Inter. J. Mol. Sci. 16: 13507-13527.   Abdul Wadood, Ghufran, M., Babar Jamal, S.B., Naeem, M., Khan, A., Ghaffar, R. (2003). Phytochemical analysis of medicinal plants occurring in local area of Mardan. Biochemistry and Analy. Biochem. 2:144.   Aguoru, C.U., Manyi, M., Okoh, T. (2009). Problems of common names in plants taxonomy. Undergraduate practical manual: univers ... Continue Reading