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SYNERGISTIC EFFECT OF BACTERIOCIN-LIKE INHIBITORY SUBSTANCES PRODUCED BY VAGINAL Lactobacillus AGAINST GROUP B Streptococci
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ABSRACT - [ Total Page(s): 1 ]The vaginal normal flora of a healthy woman is dominated by species of Lactobacillus. The balance between the vaginal flora is maintained by the protective antagonizing compounds produced by Lactobacillus. Group B Streptococci (GBS) is an opportunistic organism usually carried asymptomatically by pregnant women but cause severe neonatal infections. Antibiotics chemotherapy poses a lot of threat especially to pregnant women. Thus, this study was aimed at evaluating the antimicrobial activity of bacteriocin-like inhibitory substance produced by vaginal Lactobacillus of pregnant women on GBS. Ide
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CHAPTER ONE - [ Total Page(s): 1 ]CHAPTER ONEINTRODUCTION1.1 IntroductionBacteriocins are defined as ribosomally synthesized antimicrobial peptides which are generally active against microorganisms closely related to the producer strain (Turovskiy et al., 2009). The term bacteriocin-like substance is applied to antagonistic substances that arenot completely defined or do not fit the typical criteria of bacteriocins. They have been reported to inhibit a wide range of both Gram-positive and Gram-negative bacteria as well as fungi (Ocanaet al., 1999). They function mainly by creating pores across bacterial cell me ... Continue Reading
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ABSRACT - [ Total Page(s): 1 ]The vaginal normal flora of a healthy woman is dominated by species of Lactobacillus. The balance between the vaginal flora is maintained by the protective antagonizing compounds produced by Lactobacillus. Group B Streptococci (GBS) is an opportunistic organism usually carried asymptomatically by pregnant women but cause severe neonatal infections. Antibiotics chemotherapy poses a lot of threat especially to pregnant women. Thus, this study was aimed at evaluating the antimicrobial activity of bacteriocin-like inhibitory substance produced by vaginal Lactobacillus of pregnant women on GBS. Ide
... Continue Reading
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