• The Incidence Of Hiv In Blood Donors

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    • 1.3   OBJECTIVE OF THE STUDY
      The general objective of this study is to determine the incidence of HIV in blood donors at Shanahan Hospital Nsukka in Enugu state. Other specific objectives are:
      a.   To test for the presence of HIV antibody in donors serum or plasma.
      b.   To determine the possible way of transmitting HIV/AIDs.
      c.   To detect whether the incidence of HIV in blood donors is more in males than in females.
      1.4   SIGNIFICANCE OF THE STUDY
      This study which have bothered much on screening of human plasma or serum is not significant importance to all personal involved in these project work. It also serves as a useful supplement to all laboratory scientists that shall be adopted in any sphere for the control of the incidence of HIV/AIDs in blood donors.
      1.5   LIMITATION OF THE STUDY
      The major problem of this work is the high cost of the latex reagent used for screening. Also financial problem have contributed in limiting my case study area to Nsukka zone rather than Enugu state.
      1.6   HYPOTHESIS
      Null Hypothesis (Ho)
      Ho:    There is no significant difference in the incidence of HIV between male and female blood donors in Nsukka Local       Government Area.
      Hi:    There is significant difference in the incidence of HIV      between male and female blood donors in Nsukka Local       Government Area.
      1.7   DEFINITIONS OF TERMS
      ARC          -       Aids related complex
      ARV          -       Antiretroviral
      AIDS                 -       Acquired immunodeficiency syndrome
      HIV           -       Human immunodeficiency virus
      HAART      -       Highly active antiretroviral therapy.
      CDt4 or T4 cell     -       Subset of  T lymphocyte which help to                                 initiative immune system.
      STI                   -       Sexual transmitted infection
      PCP                   -       Pneumocustic carinii pneumonia
      TB                    -       tuberculosis
      IL- 2                 -       stimulates CDt4 production
      GP41                  -       Glycoprotein with weight of 41.
      KS                    -       Kaposi sarcoma (Tumor)
      Lumphadenopathy -    Enlargement of lumph mode
      Pathophysiology     -    The Replication process of HIV in the body
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    • ABSRACT - [ Total Page(s): 1 ]This study of the incidence of HIV in blood donors was carried out at Bishop Shanahan Hospital Nsukka of Enugu state, Nigeria. Blood samples from two hundred donors were collected examined and analyzed for HIV positive result showed that 12% of the total number of donors were seropositive. Comprising of male and female donors. When tested statistically using chi-square distribution, the result showed that there is no significance difference in the incidence of HIV between the male and female don ... Continue reading---